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Profiling the Antimalarial Mechanism of Artemisinin by Identifying Crucial Target Proteins Article

Peng Gao, Jianyou Wang, Jiayun Chen, Liwei Gu, Chen Wang, Liting Xu, Yin Kwan Wong, Huimin Zhang, Chengchao Xu, Lingyun Dai, Jigang Wang

Engineering 2023, Volume 31, Issue 12,   Pages 86-97 doi: 10.1016/j.eng.2023.06.001

Abstract: significant progress has been achieved in elucidating the antimalarial mechanisms of ART, the most crucial target

Keywords： Artemisinin     Antimalaria     Target identification     MS-CETSA     Transcriptomics    

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Feasibility study of the transient electromagnetic method for chamber blasting misfire detection and recognition

Liu Liansheng,Liang Longhua,Wu Jiyang, Jiao Yongbin,Lu Zhexiang

Strategic Study of CAE 2014, Volume 16, Issue 11,   Pages 107-112

Abstract: change of the conductive body eddy current field, realizes the cavern blasting blind shot detection and identificationThe test results show that the target when the aluminum box buried depth of no more than 30 m, transient

Keywords： Transient electromagnetic methods     Chamber blasting     Misfire detection and identification     Eddy currentfield     Target。    

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Multi-target combinatory strategy to overcome tumor immune escape

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 208-215 doi: 10.1007/s11684-022-0922-5

Abstract: The use of several antibody drugs that target PD1/PD-L1 for various cancer treatments has been approved

Keywords： immune checkpoints     multi-target     immune escape     immune-related adverse events     combination therapy    

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Atypical pituitary hormone–target tissue axis

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 1-17 doi: 10.1007/s11684-022-0973-7

Abstract: A long-held belief is that pituitary hormones bind to their cognate receptors in classical target glandshave shown that multiple types of pituitary hormone receptors are widely expressed in non-classical targetnon-classical organs were summarized, defined by the novel concept of an “atypical pituitary hormone–targetThe continued exploration of the physiology of the “atypical pituitary hormone–target tissue axis” couldenable the identification of novel therapeutic targets for metabolic diseases.

Keywords： thyroid-stimulating hormone     follicle-stimulating hormone     luteinizing hormone     adrenocorticotrophic hormone     prolactin    

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Variational mode decomposition based modal parameter identification in civil engineering

Mingjie ZHANG, Fuyou XU

Frontiers of Structural and Civil Engineering 2019, Volume 13, Issue 5,   Pages 1082-1094 doi: 10.1007/s11709-019-0537-3

Abstract: An out-put only modal parameter identification method based on variational mode decomposition (VMD) isThe proposed identification method can straightforwardly extract the mode shape vectors using the modaldemonstrate the efficiency and highlight the superiority of the proposed method in modal parameter identificationThe proposed method is proved to be efficient and accurate in modal parameter identification for both

Keywords： modal parameter identification     variational mode decomposition     civil structure     nonlinear system     closely    

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Non-convex sparse optimization-based impact force identification with limited vibration measurements

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 3, doi: 10.1007/s11465-023-0762-2

Abstract: Impact force identification is important for structure health monitoring especially in applications involvingDifferent from the traditional direct measurement method, the impact force identification technique is> regularization often identifies false forces in non-loaded regions, interfering with the accurate identificationmml:mtext>-ADMM is applied to solve the impact force identificationSimulations and experiments are performed on a composite plate to verify the identification accuracy

Keywords： impact force identification     inverse problem     sparse regularization     under-determined condition     alternating    

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Protein phosphatase magnesium-dependent 1δ is a novel tumor marker and target in hepatocellular carcinoma

Zhi Xu,Chunxiang Cao,Haiyan Xia,Shujing Shi,Lingzhi Hong,Xiaowei Wei,Dongying Gu,Jianmin Bian,Zijun Liu,Wenbin Huang,Yixin Zhang,Song He,Nikki Pui-Yue Lee,Jinfei Chen

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 52-60 doi: 10.1007/s11684-016-0433-3

Abstract:  Overall, results suggest that PPM1D is a potential prognostic marker and therapeutic target

Keywords： PPM1D     hepatocellular carcinoma     prognosis     target therapy    

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Amodified variable rate particle filter for maneuvering target tracking

Yun-fei GUO,Kong-shuai FAN,Dong-liang PENG,Ji-an LUO,Han SHENTU

Frontiers of Information Technology & Electronic Engineering 2015, Volume 16, Issue 11,   Pages 985-994 doi: 10.1631/FITEE.1500149

Abstract: To address the problem of maneuvering target tracking, where the target trajectory has prolonged smoothCompared with conventional variable rate models, the proposed model does not need any prior knowledge of target

Keywords： Maneuvering target tracking     Prolonged smooth regions     Variable rate model     Maneuver detection    

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Lightweight design of an electric bus body structure with analytical target cascading

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 1, doi: 10.1007/s11465-022-0718-y

Abstract: newly developed multi-material electric bus body structure is examined in combination with analytical target

Keywords： electric vehicle     body in white (BIW)     lightweight     analytical target cascading (ATC)    

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The research on structural damage identification using rough set and integrated neural network

Juelong LI, Hairui LI, Jianchun XING, Qiliang YANG

Frontiers of Mechanical Engineering 2013, Volume 8, Issue 3,   Pages 305-310 doi: 10.1007/s11465-013-0259-5

Abstract:

A huge amount of information and identification accuracy in large civil engineering structural damageidentification has not been addressed yet.To efficiently solve this problem, a new damage identification method based on rough set and integratedThe decision fusion network will give the final damage identification results.The identification examples show that this method can simplify the redundant information to reduce the

Keywords： rough set     integrated neural network     damage identification     decision making fusion    

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Dynamic Target Tracking of Unmanned Aerial Vehicles Under Unpredictable Disturbances

Yanjie Chen,Yangning Wu,Limin Lan,Hang Zhong,Zhiqiang Miao,Hui Zhang,Yaonan Wang,

Engineering doi: 10.1016/j.eng.2023.05.017

Abstract: IBVS) method based on a velocity observer for an unmanned aerial vehicle (UAV) for tracking a dynamic targetthen considers the uncertainties caused by the unpredictable rotations and velocities of the dynamic targetA novel image depth model that extends the IBVS method to track a rotating target with arbitrary orientationsThe depth model ensures image feature accuracy and image trajectory smoothness in rotating target trackingThe relative velocities of the UAV and the dynamic target are estimated using the proposed velocity observer

Keywords： Unmanned aerial vehicle     Visual servoing     Velocity observer     Target tracking    

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Artificial Intelligence in Pharmaceutical Sciences Review

Mingkun Lu, Jiayi Yin, Qi Zhu, Gaole Lin, Minjie Mou, Fuyao Liu, Ziqi Pan, Nanxin You, Xichen Lian, Fengcheng Li, Hongning Zhang, Lingyan Zheng, Wei Zhang, Hanyu Zhang, Zihao Shen, Zhen Gu, Honglin Li, Feng Zhu

Engineering 2023, Volume 27, Issue 8,   Pages 37-69 doi: 10.1016/j.eng.2023.01.014

Abstract: summarizes and discusses in depth their specific applications in various stages of drug R&D, such as target

Keywords： Artificial intelligence     Machine learning     Deep learning     Target identification     Target discovery     Drug    

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Mechanical design, modeling, and identification for a novel antagonistic variable stiffness dexterous

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 3, doi: 10.1007/s11465-022-0691-5

Abstract: Experimental results of the finger joint stiffness identification and finger impact tests under different

Keywords： multifingered hand     mechanism design     robot safety     variable stiffness actuator    

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Damage identification in connections of moment frames using time domain responses and an optimization

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 4,   Pages 851-866 doi: 10.1007/s11709-021-0739-3

Abstract: In this study, an optimization-based method for joint damage identification of moment frames using theThen, the problem of joint damage identification is converted to a standard optimization problem.Then, a comparison between the proposed method and the existing damage identification method is provided

Keywords： damage identification     beam-to-column connection     time-domain response     optimization    

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A methodology of implementing target mixing ratio for asphalt mixture

Yucheng HUANG, Lun JI, Rui WEN, Ming ZHANG

Frontiers of Structural and Civil Engineering 2017, Volume 11, Issue 3,   Pages 308-314 doi: 10.1007/s11709-017-0405-y

Abstract: In order to implement the objective mix design of hot mix asphalt adequately during the construction process, the significance of objective mixing ratio was elaborated, and the variability of materials and its control method were analyzed. An engineering example is used to illustrate the debugging process of asphalt mixture batching & mixing plant and the dynamic quality management methods. The results show that the set of methods can not only implement the objective mixing ratio of hot mix asphalt adequately, but also control production during the construction process effectively.

Keywords： asphalt mixture     target mixing ratio     mix design implementation     batching & mixing plant debugging    

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Title Author Date Type Operation

Profiling the Antimalarial Mechanism of Artemisinin by Identifying Crucial Target Proteins

Peng Gao, Jianyou Wang, Jiayun Chen, Liwei Gu, Chen Wang, Liting Xu, Yin Kwan Wong, Huimin Zhang, Chengchao Xu, Lingyun Dai, Jigang Wang

Journal Article

Feasibility study of the transient electromagnetic method for chamber blasting misfire detection and recognition

Liu Liansheng,Liang Longhua,Wu Jiyang, Jiao Yongbin,Lu Zhexiang

Journal Article

Multi-target combinatory strategy to overcome tumor immune escape

Journal Article

Atypical pituitary hormone–target tissue axis

Journal Article

Variational mode decomposition based modal parameter identification in civil engineering

Mingjie ZHANG, Fuyou XU

Journal Article

Non-convex sparse optimization-based impact force identification with limited vibration measurements

Journal Article

Protein phosphatase magnesium-dependent 1δ is a novel tumor marker and target in hepatocellular carcinoma

Zhi Xu,Chunxiang Cao,Haiyan Xia,Shujing Shi,Lingzhi Hong,Xiaowei Wei,Dongying Gu,Jianmin Bian,Zijun Liu,Wenbin Huang,Yixin Zhang,Song He,Nikki Pui-Yue Lee,Jinfei Chen

Journal Article

Amodified variable rate particle filter for maneuvering target tracking

Yun-fei GUO,Kong-shuai FAN,Dong-liang PENG,Ji-an LUO,Han SHENTU

Journal Article

Lightweight design of an electric bus body structure with analytical target cascading

Journal Article

The research on structural damage identification using rough set and integrated neural network

Juelong LI, Hairui LI, Jianchun XING, Qiliang YANG

Journal Article

Dynamic Target Tracking of Unmanned Aerial Vehicles Under Unpredictable Disturbances

Yanjie Chen,Yangning Wu,Limin Lan,Hang Zhong,Zhiqiang Miao,Hui Zhang,Yaonan Wang,

Journal Article

Artificial Intelligence in Pharmaceutical Sciences

Mingkun Lu, Jiayi Yin, Qi Zhu, Gaole Lin, Minjie Mou, Fuyao Liu, Ziqi Pan, Nanxin You, Xichen Lian, Fengcheng Li, Hongning Zhang, Lingyan Zheng, Wei Zhang, Hanyu Zhang, Zihao Shen, Zhen Gu, Honglin Li, Feng Zhu

Journal Article

Mechanical design, modeling, and identification for a novel antagonistic variable stiffness dexterous

Journal Article

Damage identification in connections of moment frames using time domain responses and an optimization

Journal Article

A methodology of implementing target mixing ratio for asphalt mixture

Yucheng HUANG, Lun JI, Rui WEN, Ming ZHANG

Journal Article